Mumps Vaccine Effectiveness Against Orchitis

Mumps Vaccine Effectiveness Against Orchitis

Jane Megid, Iara A. Borges, Jonatas S. Abrahão, Giliane S. Trindade, Camila M. Appolinário, Márcio G. Ribeiro, Susan D. Allendorf, João Marcelo A.P. Antunes, André T. Silva-Fernandes, and Erna G. Kroon Author affi liations: Faculdade de Medicina Veterinária e Zootecnia–Universidade Estadual Paulista, Botucatu, São Paulo, Brazil (J. Megid, C.M. Appoliinário, M.G. Ribeiro, S.D. Allendoft, J.M.A.P...

The effectiveness of evaluating mumps vaccine effectiveness.

Matched case-control study of effectiveness of live, attenuated S79 mumps virus vaccine against clinical mumps.

Mumps virus infection is a potentially serious viral infection of childhood and early adulthood. In China, live, attenuated S(79) mumps virus vaccine has been licensed for pediatric use since 1990. There has been no assessment of its efficacy. Thus, the objective of this study was to determine the effectiveness of live, attenuated S(79) mumps virus vaccine against clinical mumps. Cases were sel...

Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediated mechanism.

We report 3 cases of orchitis following vaccination with mumps-measles-rubella (MMR) vaccine, two with an onset within 3 days following vaccination. Orchitis is a common complication of mumps infection, particularly in post-pubertal males, and is also recognized as a very rare complication of mumps vaccination. These cases, discussed together with a comprehensive review of the existing literatu...

Vaccine Effectiveness Estimates, 2004–2005 Mumps Outbreak, England

The United Kingdom and United States have recently experienced large outbreaks of mumps, which raises concerns about vaccine effectiveness. The effectiveness of the mumps component of the measles, mumps, rubella (MMR) vaccine was estimated using the screening method. In England from January 2004 through March 2005, 312 cases of mumps were reported in children eligible to have received 2 doses o...